Nefro - 25-4 - MIOLO.indd

Nefro - 24-1 MIOLO.indd

Nefro - 26-4 - MIOLO.indd

The clinical relevance: The assessment of the antigenicity of an injectable molecule for the human organism requires human patient sera due to the inherent variability of antibodies from person to person, and the inherent variation of bioactivity of antibodies within a single individual. Antibodies produced experimentally in animals give little information with regard to clinical effects of the...

Nefro - 23-4 MIOLO.indd

Renal Tubular Acidosis (RTA) is a clinical syndrome characterised by metabolic acidosis secondary to a disorder in renal acidification. The acidification may be manifested by a defect in the renal tubular reabsorption of bicarbonate and/or urinary excretion of hydrogen ion1 -3. In terms of clinical and physiopathological aspects this disease can be classified into three groups: distal RTA or ty...

Nefro - 26-3 - MIOLO.indd

We describe the case of a renal transplant recipient who presented with malaise, dry cough, severe weight loss, abdominal pain and watery diarrhoea. The laboratory workup revealed anaemia and elevated C reactive protein. Chest X-ray showed bilateral reticulonodular infiltrates, and computed tomography scan of the chest and abdomen revealed diffuse thickening of the interand intralobular septs, ...

Nefro - 26-3 - MIOLO.indd

We present a 57-year-old male chronic haemodialysis patient with a giant umbilical hernia. After two months on dialysis, incarceration of the hernia with partial intestinal obstruction occurred, and this led to severe hypoproteinaemia secondary to protein-losing enteropathy, caused by increased lymphatic pressure. These problems were resolved following surgical repair of the hernia. There are f...